Inhibitory Effect of 2′-Fluoro-5-Methyl-β-l-Arabinofuranosyl-Uracil on Duck Hepatitis B Virus Replication

The antiviral activity of 2′-fluoro-5-methyl-β-l-arabinofuranosyluracil (l-FMAU), a novel l-nucleoside analog of thymidine known to be an inhibitor of hepatitis B virus (HBV) replication in hepatoma cells (2.2.1.5 cell line), was evaluated in the duck HBV (DHBV) model. Short-term oral administration...

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Bibliographic Details
Main Authors: Aguesse-Germon, Stéphanie, Liu, Shwu-Huey, Chevallier, Michèle, Pichoud, Christian, Jamard, Catherine, Borel, Christelle, Chu, Chung K., Trépo, Christian, Cheng, Yung-Chi, Zoulim, Fabien
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
Subjects:
Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC105416/
https://ncbi.nlm.nih.gov/pubmed/9527788
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