Identification of Cryptosporidium parvum Dihydrofolate Reductase Inhibitors by Complementation in Saccharomyces cerevisiae

There is a pressing need for drugs effective against the opportunistic protozoan pathogen Cryptosporidium parvum. Folate metabolic enzymes and enzymes of the thymidylate cycle, particularly dihydrofolate reductase (DHFR), have been widely exploited as chemotherapeutic targets. Although many DHFR inh...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Brophy, Victoria Hertle, Vasquez, John, Nelson, Richard G., Forney, John R., Rosowsky, Andre, Sibley, Carol Hopkins
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2000
Onderwerpen:
Susceptibility
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC89807/
https://ncbi.nlm.nih.gov/pubmed/10722506
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items