Intracellular Metabolism of β-l-2′,3′-Dideoxyadenosine: Relevance to Its Limited Antiviral Activity

The intracellular metabolism of the β-l- enantiomer of 2′,3′-dideoxyadenosine (β-l-ddA) was investigated in HepG2 cells, human peripheral blood mononuclear cells (PBMC), and primary cultured human hepatocytes in an effort to understand the metabolic basis of its limited activity on the replication o...

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Bibliografske podrobnosti

izdano v:	Antimicrob Agents Chemother
Principais autores:	Placidi, Laurent, Cretton-Scott, Erika, Gosselin, Gilles, Pierra, Claire, Schinazi, Raymond F., Imbach, Jean-Louis, el Kouni, Mahmoud H., Sommadossi, Jean-Pierre
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 2000
Teme:	Antiviral Agents
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89782/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10722481/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.4.853-858.2000
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