Intracellular Metabolism of β-l-2′,3′-Dideoxyadenosine: Relevance to Its Limited Antiviral Activity

The intracellular metabolism of the β-l- enantiomer of 2′,3′-dideoxyadenosine (β-l-ddA) was investigated in HepG2 cells, human peripheral blood mononuclear cells (PBMC), and primary cultured human hepatocytes in an effort to understand the metabolic basis of its limited activity on the replication o...

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Bibliografiska uppgifter

I publikationen:	Antimicrob Agents Chemother
Huvudupphov:	Placidi, Laurent, Cretton-Scott, Erika, Gosselin, Gilles, Pierra, Claire, Schinazi, Raymond F., Imbach, Jean-Louis, el Kouni, Mahmoud H., Sommadossi, Jean-Pierre
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	American Society for Microbiology (ASM) 2000
Ämnen:	Antiviral Agents
Länkar:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89782/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10722481/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.4.853-858.2000
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