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Contribution of Topoisomerase IV and DNA Gyrase Mutations in Streptococcus pneumoniae to Resistance to Novel Fluoroquinolones

In this study, we assessed the activity of ciprofloxacin, levofloxacin, sparfloxacin, and trovafloxacin against clinical isolates of Streptococcus pneumoniae that were resistant to the less-recently developed fluoroquinolones by using defined amino acid substitutions in DNA gyrase and topoisomerase...

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Pestova, Ekaterina, Beyer, Rebecca, Cianciotto, Nicholas P., Noskin, Gary A., Peterson, Lance R.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1999
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89404/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10428926/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.8.2000
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