Anti-Human Immunodeficiency Virus Type 1 Activity, Intracellular Metabolism, and Pharmacokinetic Evaluation of 2′-Deoxy-3′-Oxa-4′-Thiocytidine

The racemic nucleoside analogue 2′-deoxy-3′-oxa-4′-thiocytidine (dOTC) is in clinical development for the treatment of human immunodeficiency virus (HIV) type 1 (HIV-1) infection. dOTC is structurally related to lamivudine (3TC), but the oxygen and sulfur in the furanosyl ring are transposed. Intrac...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: de Muys, Jean-Marc, Gourdeau, Henriette, Nguyen-Ba, Nghe, Taylor, Debra L., Ahmed, Parvin S., Mansour, Tarek, Locas, Celine, Richard, Nathalie, Wainberg, Mark A., Rando, Robert F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC89378/
https://ncbi.nlm.nih.gov/pubmed/10428900
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados