Mechanism of Action and In Vitro Activity of 1′,3′-Dioxolanylpurine Nucleoside Analogues against Sensitive and Drug-Resistant Human Immunodeficiency Virus Type 1 Variants

(−)-β-d-1′,3′-Dioxolane guanosine (DXG) and 2,6-diaminopurine (DAPD) dioxolanyl nucleoside analogues have been reported to be potent inhibitors of human immunodeficiency virus type 1 (HIV-1). We have recently conducted experiments to more fully characterize their in vitro anti-HIV-1 profiles. Antivi...

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Detalhes bibliográficos
Main Authors: Gu, Zhengxian, Wainberg, Mark A., Nguyen-Ba, Nghe, L’Heureux, Lucille, de Muys, Jean-Marc, Bowlin, Terry L., Rando, Robert F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC89486/
https://ncbi.nlm.nih.gov/pubmed/10508010
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