Pharmacokinetics of the Antiviral Agent β-d-2′,3′-Didehydro-2′,3′-Dideoxy-5-Fluorocytidine in Rhesus Monkeys

The values of the pharmacokinetic parameters of the nucleoside antiretroviral agent β-d-2′,3′-didehydro-2′,3′-dideoxy-5-fluorocytidine (D-D4FC) in rhesus monkeys were determined with a two-compartment model after the administration of a single dose. The average values for the terminal half-life, ren...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Ma, Li, Hurwitz, Selwyn J., Shi, Junxing, McAtee, Jeffrey J., Liotta, Dennis C., McClure, Harold M., Schinazi, Raymond F.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Antiviral Agents
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89084/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9925539/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.2.381
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