Pharmacokinetics of the Antiviral Agent β-d-2′,3′-Didehydro-2′,3′-Dideoxy-5-Fluorocytidine in Rhesus Monkeys

The values of the pharmacokinetic parameters of the nucleoside antiretroviral agent β-d-2′,3′-didehydro-2′,3′-dideoxy-5-fluorocytidine (D-D4FC) in rhesus monkeys were determined with a two-compartment model after the administration of a single dose. The average values for the terminal half-life, ren...

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Main Authors: Ma, Li, Hurwitz, Selwyn J., Shi, Junxing, McAtee, Jeffrey J., Liotta, Dennis C., McClure, Harold M., Schinazi, Raymond F.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 1999
Assuntos:
Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC89084/
https://ncbi.nlm.nih.gov/pubmed/9925539
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