Antiviral Activity and Pharmacokinetics of 1-(2,3-Dideoxy-2-Fluoro-β-l-Glyceropent-2-Enofuranosyl)Cytosine

1-(2,3-Dideoxy-2-fluoro-β-l-glyceropent-2-enofuranosyl)cytosine (l-2′-Fd4C) is an l-nucleoside analogue with both anti-human immunodeficiency virus (HIV) and anti-hepatitis B virus (HBV) activity with median effective concentrations of 0.12 μM in peripheral blood mononuclear cells and 0.002 μM in He...

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Autores principales: Chen, Huachun, Pai, S. Balakrishna, Hurwitz, Selwyn J., Chu, Chung K., Glazkova, Yuliya, McClure, Harold M., Feitelson, Mark, Schinazi, Raymond F.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
Materias:
Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC155827/
https://ncbi.nlm.nih.gov/pubmed/12760868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.6.1922-1928.2003
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