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In Vitro Reconstitution of the End Replication Problem

The end replication problem hypothesis proposes that the ends of linear DNA cannot be replicated completely during lagging strand DNA synthesis. Although the idea has been widely accepted for explaining telomere attrition during cell proliferation, it has never been directly demonstrated. In order t...

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Detalhes bibliográficos
Main Authors: Ohki, Rieko, Tsurimoto, Toshiki, Ishikawa, Fuyuki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC87295/
https://ncbi.nlm.nih.gov/pubmed/11486015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.17.5753-5766.2001
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