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Telomere-bound TRF1 and TRF2 stall the replication fork at telomeric repeats

Vertebrate telomeres consist of tandem repeats of T(2)AG(3) and associated proteins including the telomeric DNA-binding proteins, TRF1 and TRF2. It has been proposed that telomeres assume two interswitchable states, the open state that is accessible to various trans-acting factors and the closed sta...

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Publicat a:Nucleic Acids Res
Autors principals: Ohki, Rieko, Ishikawa, Fuyuki
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC390322/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15007108/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh309
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