Control of Human Telomere Length by TRF1 and TRF2

Telomere length in human cells is controlled by a homeostasis mechanism that involves telomerase and the negative regulator of telomere length, TRF1 (TTAGGG repeat binding factor 1). Here we report that TRF2, a TRF1-related protein previously implicated in protection of chromosome ends, is a second...

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Bibliographic Details
Main Authors: Smogorzewska, Agata, van Steensel, Bas, Bianchi, Alessandro, Oelmann, Stefan, Schaefer, Matthias R., Schnapp, Gisela, de Lange, Titia
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
DNA Dynamics and Chromosome Structure
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC85349/
https://ncbi.nlm.nih.gov/pubmed/10669743
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