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In Vitro Reconstitution of the End Replication Problem
The end replication problem hypothesis proposes that the ends of linear DNA cannot be replicated completely during lagging strand DNA synthesis. Although the idea has been widely accepted for explaining telomere attrition during cell proliferation, it has never been directly demonstrated. In order t...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2001
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC87295/ https://ncbi.nlm.nih.gov/pubmed/11486015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.17.5753-5766.2001 |
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