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In Vitro Reconstitution of the End Replication Problem

The end replication problem hypothesis proposes that the ends of linear DNA cannot be replicated completely during lagging strand DNA synthesis. Although the idea has been widely accepted for explaining telomere attrition during cell proliferation, it has never been directly demonstrated. In order t...

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書誌詳細
主要な著者: Ohki, Rieko, Tsurimoto, Toshiki, Ishikawa, Fuyuki
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2001
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC87295/
https://ncbi.nlm.nih.gov/pubmed/11486015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.17.5753-5766.2001
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