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In Vitro Reconstitution of the End Replication Problem

The end replication problem hypothesis proposes that the ends of linear DNA cannot be replicated completely during lagging strand DNA synthesis. Although the idea has been widely accepted for explaining telomere attrition during cell proliferation, it has never been directly demonstrated. In order t...

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Библиографические подробности
Главные авторы: Ohki, Rieko, Tsurimoto, Toshiki, Ishikawa, Fuyuki
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2001
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC87295/
https://ncbi.nlm.nih.gov/pubmed/11486015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.17.5753-5766.2001
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