Reduced Hepatic Uptake and Intestinal Excretion of Organic Cations in Mice with a Targeted Disruption of the Organic Cation Transporter 1 (Oct1 [Slc22a1]) Gene

The polyspecific organic cation transporter 1 (OCT1 [SLC22A1]) mediates facilitated transport of small (hydrophilic) organic cations. OCT1 is localized at the basolateral membrane of epithelial cells in the liver, kidney, and intestine and could therefore be involved in the elimination of endogenous...

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Xehetasun bibliografikoak
Egile Nagusiak: Jonker, Johan W., Wagenaar, Els, Mol, Carla A. A. M., Buitelaar, Marije, Koepsell, Hermann, Smit, Johan W., Schinkel, Alfred H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2001
Gaiak:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC87269/
https://ncbi.nlm.nih.gov/pubmed/11463829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.16.5471-5477.2001
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