Reduced Hepatic Uptake and Intestinal Excretion of Organic Cations in Mice with a Targeted Disruption of the Organic Cation Transporter 1 (Oct1 [Slc22a1]) Gene

The polyspecific organic cation transporter 1 (OCT1 [SLC22A1]) mediates facilitated transport of small (hydrophilic) organic cations. OCT1 is localized at the basolateral membrane of epithelial cells in the liver, kidney, and intestine and could therefore be involved in the elimination of endogenous...

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Detaylı Bibliyografya
Asıl Yazarlar: Jonker, Johan W., Wagenaar, Els, Mol, Carla A. A. M., Buitelaar, Marije, Koepsell, Hermann, Smit, Johan W., Schinkel, Alfred H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2001
Konular:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC87269/
https://ncbi.nlm.nih.gov/pubmed/11463829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.16.5471-5477.2001
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