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SIR Functions Are Required for the Toleration of an Unrepaired Double-Strand Break in a Dispensable Yeast Chromosome

Unrepaired DNA double-strand breaks (DSBs) typically result in G(2) arrest. Cell cycle progression can resume following repair of the DSBs or through adaptation to the checkpoint, even if the damage remains unrepaired. We developed a screen for factors in the yeast Saccharomyces cerevisiae that affe...

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Udgivet i:Mol Cell Biol
Principais autores: Bennett, Craig B., Snipe, Joyce R., Westmoreland, James W., Resnick, Michael A.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2001
Fag:
DNA Dynamics and Chromosome Structure
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87259/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11463819/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.16.5359-5373.2001
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