SIR Functions Are Required for the Toleration of an Unrepaired Double-Strand Break in a Dispensable Yeast Chromosome

Unrepaired DNA double-strand breaks (DSBs) typically result in G(2) arrest. Cell cycle progression can resume following repair of the DSBs or through adaptation to the checkpoint, even if the damage remains unrepaired. We developed a screen for factors in the yeast Saccharomyces cerevisiae that affe...

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Detalhes bibliográficos
Main Authors: Bennett, Craig B., Snipe, Joyce R., Westmoreland, James W., Resnick, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
DNA Dynamics and Chromosome Structure
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC87259/
https://ncbi.nlm.nih.gov/pubmed/11463819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.16.5359-5373.2001
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