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Use of yeast artificial chromosomes (YACs) in studies of mammalian development: production of beta-globin locus YAC mice carrying human globin developmental mutants.

To test whether yeast artificial chromosomes (YACs) can be used in the investigation of mammalian development, we analyzed the phenotypes of transgenic mice carrying two types of beta-globin locus YAC developmental mutants: (i) mice carrying a G-->A transition at position -117 of the A gamma gene, w...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Peterson, K R, Li, Q L, Clegg, C H, Furukawa, T, Navas, P A, Norton, E J, Kimbrough, T G, Stamatoyannopoulos, G
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41755/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7539923/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.12.5655
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