Use of yeast artificial chromosomes (YACs) in studies of mammalian development: production of beta-globin locus YAC mice carrying human globin developmental mutants.

To test whether yeast artificial chromosomes (YACs) can be used in the investigation of mammalian development, we analyzed the phenotypes of transgenic mice carrying two types of beta-globin locus YAC developmental mutants: (i) mice carrying a G-->A transition at position -117 of the A gamma gene...

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Hauptverfasser: Peterson, K R, Li, Q L, Clegg, C H, Furukawa, T, Navas, P A, Norton, E J, Kimbrough, T G, Stamatoyannopoulos, G
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1995
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC41755/
https://ncbi.nlm.nih.gov/pubmed/7539923
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