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Investigations of a Human Embryonic Globin Gene Silencing Element Using YAC Transgenic Mice

A silencing element has been previously located upstream of the human ε-globin gene promoter using transient assays and transgenic mice carrying plasmid constructs in which the element has been deleted or its transcriptional motifs have been mutated. To investigate whether this element functions in...

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Main Authors: Navas, Patrick A., Li, Qiliang, Peterson, Kenneth R., Stamatoyannopoulos, George
格式: Artigo
語言:Inglês
出版: 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812921/
https://ncbi.nlm.nih.gov/pubmed/16514181
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