Developmental Specificity of the Interaction between the Locus Control Region and Embryonic or Fetal Globin Genes in Transgenic Mice with an HS3 Core Deletion

The human β-globin locus control region (LCR) consists of five erythroid-lineage-specific DNase I-hypersensitive sites (HSs) and is required for activation of the β-globin locus chromatin domain and globin gene expression. Each DNase I-HS of the LCR consists of a highly conserved core element and fl...

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Bibliographische Detailangaben
Hauptverfasser: Navas, Patrick A., Peterson, Kenneth R., Li, Qiliang, Skarpidi, Eva, Rohde, Alex, Shaw, Sara E., Clegg, Christopher H., Asano, Haruhiko, Stamatoyannopoulos, George
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1998
Schlagworte:
Gene Expression
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC109003/
https://ncbi.nlm.nih.gov/pubmed/9632803
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