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Developmental Specificity of the Interaction between the Locus Control Region and Embryonic or Fetal Globin Genes in Transgenic Mice with an HS3 Core Deletion

The human β-globin locus control region (LCR) consists of five erythroid-lineage-specific DNase I-hypersensitive sites (HSs) and is required for activation of the β-globin locus chromatin domain and globin gene expression. Each DNase I-HS of the LCR consists of a highly conserved core element and fl...

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Détails bibliographiques
Publié dans:Mol Cell Biol
Auteurs principaux: Navas, Patrick A., Peterson, Kenneth R., Li, Qiliang, Skarpidi, Eva, Rohde, Alex, Shaw, Sara E., Clegg, Christopher H., Asano, Haruhiko, Stamatoyannopoulos, George
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 1998
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109003/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9632803/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.7.4188
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