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Human beta-globin locus control region: analysis of the 5' DNase I hypersensitive site HS 2 in transgenic mice.

The human beta-globin locus control region (LCR) is essential for high-level expression of human epsilon-, gamma-, and beta-globin genes. Developmentally stable DNase I hypersensitive sites (designated HS) mark sequences within this region that are important for LCR activity. A 1.9-kilobase (kb) fra...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Caterina, J J, Ryan, T M, Pawlik, K M, Palmiter, R D, Brinster, R L, Behringer, R R, Townes, T M
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51077/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2000371/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.5.1626
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