Human beta-globin locus control region: analysis of the 5' DNase I hypersensitive site HS 2 in transgenic mice.
The human beta-globin locus control region (LCR) is essential for high-level expression of human epsilon-, gamma-, and beta-globin genes. Developmentally stable DNase I hypersensitive sites (designated HS) mark sequences within this region that are important for LCR activity. A 1.9-kilobase (kb) fra...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1991
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51077/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2000371/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.5.1626 |
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