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Recombination during transformation as a source of chimeric mammalian artificial chromosomes in yeast (YACs).
Mammalian DNAs cloned as artificial chromosomes in yeast (YACs) frequently are chimeras formed between noncontiguous DNAs. Using pairs of human and mouse YACs we examined the contribution of recombination during transformation or subsequent mitotic growth to chimeric YAC formation. The DNA from pair...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1994
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC331905/ https://ncbi.nlm.nih.gov/pubmed/7937141 |
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