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Axin Facilitates Smad3 Activation in the Transforming Growth Factor β Signaling Pathway
Axin acts as a negative regulator in Wnt signaling through interaction with various molecules involved in this pathway, including β-catenin, adenomatous polyposis coli, and glycogen synthase kinase 3β. We show here that Axin also regulates the effects of Smad3 on the transforming growth factor β (TG...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2001
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC87238/ https://ncbi.nlm.nih.gov/pubmed/11438668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.15.5132-5141.2001 |
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