Desumoylation Activity of Axam, a Novel Axin-Binding Protein, Is Involved in Downregulation of β-Catenin

Axam has been identified as a novel Axin-binding protein that inhibits the Wnt signaling pathway. We studied the molecular mechanism by which Axam stimulates the downregulation of β-catenin. The C-terminal region of Axam has an amino acid sequence similar to that of the catalytic region of SENP1, a...

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Detalhes bibliográficos
Main Authors: Kadoya, Takayuki, Yamamoto, Hideki, Suzuki, Toshiaki, Yukita, Akira, Fukui, Akimasa, Michiue, Tatsuo, Asahara, Toshimasa, Tanaka, Keiji, Asashima, Makoto, Kikuchi, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC133821/
https://ncbi.nlm.nih.gov/pubmed/11997515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.11.3803-3819.2002
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