Desumoylation Activity of Axam, a Novel Axin-Binding Protein, Is Involved in Downregulation of β-Catenin

Axam has been identified as a novel Axin-binding protein that inhibits the Wnt signaling pathway. We studied the molecular mechanism by which Axam stimulates the downregulation of β-catenin. The C-terminal region of Axam has an amino acid sequence similar to that of the catalytic region of SENP1, a...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Kadoya, Takayuki, Yamamoto, Hideki, Suzuki, Toshiaki, Yukita, Akira, Fukui, Akimasa, Michiue, Tatsuo, Asahara, Toshimasa, Tanaka, Keiji, Asashima, Makoto, Kikuchi, Akira
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2002
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133821/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11997515/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.11.3803-3819.2002
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