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Inhibition of the Wnt Signaling Pathway by Idax, a Novel Dvl-Binding Protein

In attempting to clarify the roles of Dvl in the Wnt signaling pathway, we identified a novel protein which binds to the PDZ domain of Dvl and named it Idax (for inhibition of the Dvl and Axin complex). Idax and Axin competed with each other for the binding to Dvl. Immunocytochemical analyses showed...

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Detalhes bibliográficos
Main Authors: Hino, Shin-ichiro, Kishida, Shosei, Michiue, Tatsuo, Fukui, Akimasa, Sakamoto, Ikuo, Takada, Shinji, Asashima, Makoto, Kikuchi, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC88806/
https://ncbi.nlm.nih.gov/pubmed/11113207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.1.330-342.2001
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