Axil, a Member of the Axin Family, Interacts with Both Glycogen Synthase Kinase 3β and β-Catenin and Inhibits Axis Formation of Xenopus Embryos

Using a yeast two-hybrid method, we identified a novel protein which interacts with glycogen synthase kinase 3β (GSK-3β). This protein had 44% amino acid identity with Axin, a negative regulator of the Wnt signaling pathway.We designated this protein Axil for Axin like. Like Axin, Axil ventralized X...

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Bibliographische Detailangaben
Hauptverfasser: Yamamoto, Hideki, Kishida, Shosei, Uochi, Takaaki, Ikeda, Satoshi, Koyama, Shinya, Asashima, Makoto, Kikuchi, Akira
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1998
Schlagworte:
Cell Growth and Development
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC110665/
https://ncbi.nlm.nih.gov/pubmed/9566905
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