Axin Facilitates Smad3 Activation in the Transforming Growth Factor β Signaling Pathway

Axin acts as a negative regulator in Wnt signaling through interaction with various molecules involved in this pathway, including β-catenin, adenomatous polyposis coli, and glycogen synthase kinase 3β. We show here that Axin also regulates the effects of Smad3 on the transforming growth factor β (TG...

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Détails bibliographiques
Auteurs principaux: Furuhashi, Masao, Yagi, Ken, Yamamoto, Hideki, Furukawa, Yoichi, Shimada, Shinji, Nakamura, Yusuke, Kikuchi, Akira, Miyazono, Kohei, Kato, Mitsuyasu
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2001
Sujets:
Cell Growth and Development
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC87238/
https://ncbi.nlm.nih.gov/pubmed/11438668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.15.5132-5141.2001
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