Differential Regulation of Retinoblastoma Tumor Suppressor Protein by G(1) Cyclin-Dependent Kinase Complexes In Vivo

The retinoblastoma tumor suppressor protein (pRB) negatively regulates early-G(1) cell cycle progression, in part, by sequestering E2F transcription factors and repressing E2F-responsive genes. Although pRB is phosphorylated on up to 16 cyclin-dependent kinase (Cdk) sites by multiple G(1) cyclin-Cdk...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Ezhevsky, Sergei A., Ho, Alan, Becker-Hapak, Michelle, Davis, Penny K., Dowdy, Steven F.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2001
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87164/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11416152/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.14.4773-4784.2001
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