RB-Dependent S-Phase Response to DNA Damage

The retinoblastoma tumor suppressor protein (RB) is a potent inhibitor of cell proliferation. RB is expressed throughout the cell cycle, but its antiproliferative activity is neutralized by phosphorylation during the G(1)/S transition. RB plays an essential role in the G(1) arrest induced by a varie...

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Detalhes bibliográficos
Main Authors: Knudsen, Karen E., Booth, Dana, Naderi, Soheil, Sever-Chroneos, Zvjezdana, Fribourg, Anne F., Hunton, Irina C., Feramisco, James R., Wang, Jean Y. J., Knudsen, Erik S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC86358/
https://ncbi.nlm.nih.gov/pubmed/11003670
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