Sequences Flanking Hypersensitive Sites of the β-Globin Locus Control Region Are Required for Synergistic Enhancement

The major distal regulatory sequence for the β-globin gene locus, the locus control region (LCR), is composed of multiple hypersensitive sites (HSs). Different models for LCR function postulate that the HSs act either independently or synergistically. To test these possibilities, we have constructed...

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Detaylı Bibliyografya
Asıl Yazarlar: Molete, Joseph M., Petrykowska, Hanna, Bouhassira, Eric E., Feng, Yong-Qing, Miller, Webb, Hardison, Ross C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2001
Konular:
Transcriptional Regulation
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC86926/
https://ncbi.nlm.nih.gov/pubmed/11287603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.9.2969-2980.2001
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