Sequences Flanking Hypersensitive Sites of the β-Globin Locus Control Region Are Required for Synergistic Enhancement

The major distal regulatory sequence for the β-globin gene locus, the locus control region (LCR), is composed of multiple hypersensitive sites (HSs). Different models for LCR function postulate that the HSs act either independently or synergistically. To test these possibilities, we have constructed...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Molete, Joseph M., Petrykowska, Hanna, Bouhassira, Eric E., Feng, Yong-Qing, Miller, Webb, Hardison, Ross C.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2001
Sujets:
Transcriptional Regulation
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC86926/
https://ncbi.nlm.nih.gov/pubmed/11287603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.9.2969-2980.2001
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires