Sequences Flanking Hypersensitive Sites of the β-Globin Locus Control Region Are Required for Synergistic Enhancement

The major distal regulatory sequence for the β-globin gene locus, the locus control region (LCR), is composed of multiple hypersensitive sites (HSs). Different models for LCR function postulate that the HSs act either independently or synergistically. To test these possibilities, we have constructed...

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Библиографические подробности

Опубликовано в::	Mol Cell Biol
Главные авторы:	Molete, Joseph M., Petrykowska, Hanna, Bouhassira, Eric E., Feng, Yong-Qing, Miller, Webb, Hardison, Ross C.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Taylor & Francis 2001
Предметы:	Transcriptional Regulation
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86926/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11287603/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.9.2969-2980.2001
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