Inactivation of DNA Mismatch Repair by Increased Expression of Yeast MLH1
Inactivation of DNA mismatch repair by mutation or by transcriptional silencing of the MLH1 gene results in genome instability and cancer predisposition. We recently found (P. V. Shcherbakova and T. A. Kunkel, Mol. Cell. Biol. 19:3177–3183, 1999) that an elevated spontaneous mutation rate can also r...
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| Publicado no: | Mol Cell Biol |
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| Principais autores: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86684/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11154280/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.3.940-951.2001 |
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