Inactivation of DNA Mismatch Repair by Increased Expression of Yeast MLH1

Inactivation of DNA mismatch repair by mutation or by transcriptional silencing of the MLH1 gene results in genome instability and cancer predisposition. We recently found (P. V. Shcherbakova and T. A. Kunkel, Mol. Cell. Biol. 19:3177–3183, 1999) that an elevated spontaneous mutation rate can also r...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Shcherbakova, Polina V., Hall, Mark C., Lewis, Marc S., Bennett, Samuel E., Martin, Karla J., Bushel, Pierre R., Afshari, Cynthia A., Kunkel, Thomas A.
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 2001
Fag:	DNA Dynamics and Chromosome Structure
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86684/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11154280/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.3.940-951.2001
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