Inactivation of DNA Mismatch Repair by Increased Expression of Yeast MLH1
Inactivation of DNA mismatch repair by mutation or by transcriptional silencing of the MLH1 gene results in genome instability and cancer predisposition. We recently found (P. V. Shcherbakova and T. A. Kunkel, Mol. Cell. Biol. 19:3177–3183, 1999) that an elevated spontaneous mutation rate can also r...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Mol Cell Biol |
|---|---|
| Prif Awduron: | , , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Taylor & Francis
2001
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86684/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11154280/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.3.940-951.2001 |
| Tagiau: |
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