Inactivation of DNA Mismatch Repair by Increased Expression of Yeast MLH1

Inactivation of DNA mismatch repair by mutation or by transcriptional silencing of the MLH1 gene results in genome instability and cancer predisposition. We recently found (P. V. Shcherbakova and T. A. Kunkel, Mol. Cell. Biol. 19:3177–3183, 1999) that an elevated spontaneous mutation rate can also r...

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Detaylı Bibliyografya
Yayımlandı:	Mol Cell Biol
Asıl Yazarlar:	Shcherbakova, Polina V., Hall, Mark C., Lewis, Marc S., Bennett, Samuel E., Martin, Karla J., Bushel, Pierre R., Afshari, Cynthia A., Kunkel, Thomas A.
Materyal Türü:	Artigo
Dil:	Inglês
Baskı/Yayın Bilgisi:	Taylor & Francis 2001
Konular:	DNA Dynamics and Chromosome Structure
Online Erişim:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86684/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11154280/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.3.940-951.2001
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Inactivation of DNA Mismatch Repair by Increased Expression of Yeast MLH1

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