Generation of a Mouse Model for Arginase II Deficiency by Targeted Disruption of the Arginase II Gene

Mammals express two isoforms of arginase, designated types I and II. Arginase I is a component of the urea cycle, and inherited defects in arginase I have deleterious consequences in humans. In contrast, the physiologic role of arginase II has not been defined, and no deficiencies in arginase II hav...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Shi, Ou, Morris, Sidney M., Zoghbi, Huda, Porter, Carl W., O'Brien, William E.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2001
Assuntos:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86672/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11154268/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.3.811-813.2001
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