Generation of a Mouse Model for Arginase II Deficiency by Targeted Disruption of the Arginase II Gene
Mammals express two isoforms of arginase, designated types I and II. Arginase I is a component of the urea cycle, and inherited defects in arginase I have deleterious consequences in humans. In contrast, the physiologic role of arginase II has not been defined, and no deficiencies in arginase II hav...
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| Veröffentlicht in: | Mol Cell Biol |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2001
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86672/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11154268/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.3.811-813.2001 |
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