Generation of a Mouse Model for Arginase II Deficiency by Targeted Disruption of the Arginase II Gene

Mammals express two isoforms of arginase, designated types I and II. Arginase I is a component of the urea cycle, and inherited defects in arginase I have deleterious consequences in humans. In contrast, the physiologic role of arginase II has not been defined, and no deficiencies in arginase II hav...

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Bibliografiska uppgifter

I publikationen:	Mol Cell Biol
Huvudupphov:	Shi, Ou, Morris, Sidney M., Zoghbi, Huda, Porter, Carl W., O'Brien, William E.
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Taylor & Francis 2001
Ämnen:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Länkar:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86672/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11154268/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.3.811-813.2001
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