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Generation of a Mouse Model for Arginase II Deficiency by Targeted Disruption of the Arginase II Gene
Mammals express two isoforms of arginase, designated types I and II. Arginase I is a component of the urea cycle, and inherited defects in arginase I have deleterious consequences in humans. In contrast, the physiologic role of arginase II has not been defined, and no deficiencies in arginase II hav...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2001
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC86672/ https://ncbi.nlm.nih.gov/pubmed/11154268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.3.811-813.2001 |
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