Dexamethasone Destabilizes Cyclooxygenase 2 mRNA by Inhibiting Mitogen-Activated Protein Kinase p38

The stability of cyclooxygenase 2 (Cox-2) mRNA is regulated positively by proinflammatory stimuli acting through mitogen-activated protein kinase (MAPK) p38 and negatively by anti-inflammatory glucocorticoids such as dexamethasone. A tetracycline-regulated reporter system was used to investigate mec...

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Εκδόθηκε σε:	Mol Cell Biol
Κύριοι συγγραφείς:	Lasa, Marina, Brook, Matthew, Saklatvala, Jeremy, Clark, Andrew R.
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Taylor & Francis 2001
Θέματα:	Gene Expression
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86669/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11154265/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.3.771-780.2001
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