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Regulation of CDK7–Carboxyl-Terminal Domain Kinase Activity by the Tumor Suppressor p16(INK4A) Contributes to Cell Cycle Regulation
The eukaryotic cell cycle is regulated by cyclin-dependent kinases (CDKs). CDK4 and CDK6, which are activated by D-type cyclins during the G(1) phase of the cell cycle, are thought to be responsible for phosphorylation of the retinoblastoma gene product (pRb). The tumor suppressor p16(INK4A) inhibit...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology
2000
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC86351/ https://ncbi.nlm.nih.gov/pubmed/11003668 |
| タグ: |
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