Regulation of CDK7–Carboxyl-Terminal Domain Kinase Activity by the Tumor Suppressor p16(INK4A) Contributes to Cell Cycle Regulation

The eukaryotic cell cycle is regulated by cyclin-dependent kinases (CDKs). CDK4 and CDK6, which are activated by D-type cyclins during the G(1) phase of the cell cycle, are thought to be responsible for phosphorylation of the retinoblastoma gene product (pRb). The tumor suppressor p16(INK4A) inhibit...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Nishiwaki, Eiji, Turner, Saralinda L., Harju, Susanna, Miyazaki, Shiro, Kashiwagi, Masahide, Koh, James, Serizawa, Hiroaki
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2000
Θέματα:
Cell Growth and Development
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC86351/
https://ncbi.nlm.nih.gov/pubmed/11003668
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