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Tumor Suppressor p53 Is Required To Modulate BRCA1 Expression

Individuals carrying mutations in BRCA1 or p53 genes are predisposed to a variety of cancers, and both tumor suppressor genes have been implicated in DNA damage response pathways. We have analyzed a possible functional link between p53 and BRCA1 genes. Here we show that BRCA1 expression levels are d...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Arizti, Paz, Fang, Li, Park, Iha, Yin, Yuxin, Solomon, Ellen, Ouchi, Toru, Aaronson, Stuart A., Lee, Sam W.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2000
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86298/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11003642/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.20.7450-7459.2000
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